Imperial College London’s Department of Life Sciences invites you to attend the Sir Ernst Chain Annual Lecture. The lecture will be delivered by Sir Gregory Winter, MRC Laboratory of Molecular Biology, Cambridge, winner of the 2018 Nobel Prize in Chemistry.
A tale of two antibodies
Date: Wednesday 2 July 2025
Time: 17.30 – 18.30 BST
Lecture venue: Lecture Theatre 200, City and Guilds Building, Imperial College London, South Kensington, SW7 2AE. (see square B2 on the map)
Live stream: Please note that there is no live stream provision for this lecture.
Please register to attend the lecture here
We have limited spaces available, so please ensure you register for this lecture in advance via the link above.
The lecture will be followed by a public reception until 19.30.
Abstract
In recent years we have seen a revolution in the development of monoclonal antibodies as game-changing pharmaceutical drugs. As one of its ringleaders, Sir Gregory Winter will take us on a journey through the development of two antibodies, alemtuzumab and adalimumab, telling us the story of the interplay of technology, intellectual property, business and politics that shaped this amazing breakthrough.
Biography
Sir Gregory Winter CBE FRS FMedSci is a Nobel Prize-winning English molecular biologist best known for his work on the therapeutic use of monoclonal antibodies. His research career has been based almost entirely at the MRC Laboratory of Molecular Biology and the MRC Centre for Protein Engineering, in Cambridge, England.
He is credited with having invented techniques to both humanize and, later, to fully humanize using phage display, antibodies for therapeutic uses. Previously, antibodies had been derived from mice, which made them difficult to use in human therapeutics because the human immune system had anti-mouse reactions to them. For these developments Winter was awarded the 2018 Nobel Prize in Chemistry along with George Smith and Frances Arnold.
Sir Ernst Chain Lecture
The Sir Ernst Chain Lecture is an annual event held by Imperial’s Department of Life Sciences, commemorating the achievements of Sir Ernst Chain for humankind. In 1945 Ernst Chain, Alexander Fleming and Howard Florey received the Nobel Prize for Physiology or Medicine for the discovery and isolation of penicillin. Fleming made the original famous observation of the production of an “anti-bacterial agent” at St Mary’s, but it was Ernst Chain who developed the process to isolate penicillin.
Further details will be sent out in the joining instructions ahead of the event. If you have any questions in the meantime, please email rsvp@imperial.ac.uk

Read Sir Ernst Chain Annual Lecture: A tale of two antibodies (2 July) in full